Opaleye, L.P.

Opaleye, L.P. is reported as a hedge fund in Form ADV private-fund disclosures. The adviser is Opaleye Management Inc., based in Boston, Massachusetts, United States.

General hedge fund $500M to $1B $1M to $5M minimum

$789.2Mgross assets

$1.0Mminimum

63owners

3(c)(1)exemption

Disclosure fields

Fund facts

SEC private fund ID805-3446417957

Reference ID1637

JurisdictionDelaware, United States

Fund of fundsNo

Master fundNo

Feeder fundNo

Non-US ownership1%

Assets valued97%

Annual auditYes

GAAPYes

Source periodFebruary 2026

Date submitted02/19/2026 10:17:13 AM

Adviser

Opaleye Management Inc.

TypeRegistered investment adviser

SEC number801-78700

CRD124513

Regulatory AUM$802.8M

Compliance signals

Exempt from registration Sales limited Prime brokers reported Custodians reported

Service providers

Reported counterparties

General partners

James SilvermanOpaleye Gp LLC

Auditors

APRIO ADVISORY GROUP

Prime brokers

BTIG, LLCINTERACTIVE BROKERS LLC

Custodians

BTIG, LLCINTERACTIVE BROKERS LLC

Administrators

FINANCIAL SOLUTIONS ACCOUNTING AND ADMINISTRATIVE SERVICES, INC